Statin muscle-related adverse events - UpToDate
2024年7月8日 · Statins are both effective and generally safe. Although muscle toxicity remains a concern, severe myonecrosis leading to clinical rhabdomyolysis is rare, affecting perhaps 0.1 percent of patients . Muscle syndromes associated with statins include myalgias, myopathy, myositis, and muscle injury .
Statin-Induced Myopathy: Types, Symptoms, and Risk Factors - Healthline
2022年5月16日 · Statin-induced myopathy is pain caused by statin medications that reduce risk of heart disease. We explain causes, symptoms, treatment, etc.
Managing Statin-Associated Muscle Symptoms
2017年5月3日 · Resources such as the National Lipid Association’s Statin Myalgia Clinical Index Score focus on location, symmetry, and timing of muscle pain as well as response to dechallenge and challenge, producing statin myalgia likelihood score.
What to Know About Statin-Induced Myopathy (Muscle Pain) - HealthCentral
2024年7月18日 · Statin-induced myopathy is muscle weakness or pain due to use of a cholesterol-lowering statin medication, potentially caused by muscle inflammation or damage.
Managing statin muscle pain - Harvard Health
2019年8月9日 · Pain. Managing statin muscle pain. August 9, 2019. There are several things you can do to prevent or minimize the aches and pains that might accompany statin use. If you're not taking a statin now, you may well be soon.
Risks and Management of Muscle Pain in Statin Users - Verywell …
2024年3月19日 · So-called statin-associated muscle symptoms (SAMS)—including myalgia (generalized muscle pain) and myopathy (diseases that cause muscle weakness)—are notable ones. Muscle pain associated with statins may be mild, uncomfortable, or significant enough to impact daily life.
1.5-3% of statin users in randomised controlled trials and up to 10-13% of participants enrolled in prospec- tive clinical studies develop myalgia. 1-4 As a conserva-
Statin-Associated Myopathy: Emphasis on Mechanisms and …
Pain threshold can be a determinant for statin-related myopathy when myalgia is a diagnostic criterion. Genetic variants of serotonin receptors 3B and 7 (namely rs2276307 and rs1935349) are significantly related to myalgia score, but not to serum CK levels .
Statin-induced myopathy: Definition, symptoms and treatment
2023年11月21日 · Statins are cholesterol-lowering medications that can help reduce a person’s risk of heart attack and stroke. A side effect of statins that some people report is myopathy, a group of disorders ...
Toward “Pain-Free” Statin Prescribing: Clinical Algorithm for …
This review delineates the scope of statin-related myalgia, myopathy, and rhabdomyolysis on the basis of findings from recent meta-analyses, cohort trials, and clinical trials and of analyses of Food and Drug Administration (FDA) data; explores the clinical effects of statin-associated muscle symptoms; and outlines diagnostic and management ...