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  1. A time-resolved multi-omic atlas of the developing mouse …

    • To map the proteomic atlas of the developing mouse stomach, we collected three replicates of whole stomach organs at 15 timepoints that covered embryonic days (E12.5, embryonic day 12.5; E13.5, embryonic d… 展开

    Three Distinct Phases of The Developing Mouse Stomach

    The development of the stomach is tightly regulated by a series of signaling events and clusters of effectors on key pathways to control endoderm patterning, gastric specification, sto… 展开

    Nature
    Dynamics of Key Gastric Proteins During Stomach Development

    As a major digestive organ, the stomach produces many digestive enzymes to breakdown f… 展开

    Nature
    Identification of Differentially Expressed Splicing Isoforms

    In parallel with MS-based proteomics, we also carried out high-throughput RNA-Seq on mouse stomach tissues collected at the same timepoints. Our data analysis pipeline enabled the iden… 展开

    Nature
    Protein–Rna Correlation and Novel Splice-Junction Events

    Recently, genomic and proteomic studies have suggested that the levels of protein and mRNA are not well-correlated despite the fact that proteins are translated from mRNA52. For thi… 展开

    Nature
    Correlation of Stomach Development and Gastric Cancer

    Tumorigenesis has been suggested to resemble a mis-regulated embryonic development process in a variety of ways31, and this view is supported by experimental evi… 展开

    Nature