In genetics, chromosome translocation is a phenomenon that results in unusual rearrangement of chromosomes. This includes balanced and unbalanced translocation, with two main types: reciprocal , and Robertsonian translocation.

Dec 2, 2024 · Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant...

5 days ago · A translocation, as related to genetics, occurs when a chromosome breaks and the (typically two) fragmented pieces re-attach to different chromosomes. The detection of chromosomal translocations can be important for the diagnosis of …

If a chromosome break occurs in each of two nonhomologous chromosomes and the two breaks rejoin in a new arrangement, the new segment is called a translocation. A cell bearing a heterozygous translocation has a full set of genes and will be viable unless…

Chromosome translocations are catastrophic genomic events and often play key roles in tumorigenesis. Yet the biogenesis of chromosome translocations is remarkably poorly understood. Recent work has delineated several distinct mechanistic steps in ...

Translocations have been induced through various physical and chemical mutagens in several plant and animal species. Translocations originate through chromosome breakage and reunion. It can also be interpreted on the basis of exchange model.

Translocations are simple “cut and paste” structural genome variants (SVs) that can arise when there are two co-existing breaks on different chromosomes, and the incorrect ends are joined together (i.e. an end from one chromosome is joined to an end from a different chromosome).

Chromosomal translocations are products of the illegitimate repair of DNA double-strand breaks (DSBs). Their formation can bring about significant structural and molecular changes in the cell that can be physiologically and pathologically relevant. The induced changes may lead to serious and life-threatening diseases such as cancer.

Nov 1, 2023 · Translocation means a change in location. It often refers to genetics, when part of a chromosome is transferred to another chromosome. Chromosomes are structures that carry genes, our units of heredity.

Apr 1, 2014 · Chromosome translocations are catastrophic genomic events and often play key roles in tumorigenesis. Yet the biogenesis of chromosome translocations is remarkably poorly understood.