The umbilical cord: a rich and ethical stem cell source to advance ...
Umbilical cord blood has been used clinically for over 20 years as a cell source for haematopoietic stem cell transplantation. Beyond this, cord blood and umbilical cord‐derived stem cells have demonstrated potential for pluripotent lineage differentiation (liver, pancreatic, neural tissues and more) in vitro and in vivo .
Overview of Umbilical Cord Blood - Stanford Medicine
Umbilical cord blood is a rich source of hematopoietic, or blood-forming, stem cells. Hematopoietic stem cells can develop into all three types of blood cells (RBCs, WBCs and platelets) and hold the potential to reconstitute an individual’s entire blood supply.
Stem Cells in the Umbilical Cord - PMC - PubMed Central (PMC)
This review will focus on the umbilical cord-derived stem cells and compare those cells with adult bone marrow-derived mesenchymal stem cells. Index Entries: Umbilical cord matrix cells, Wharton’s Jelly, mesenchymal stem cells, umbilical cord blood cells
Prospects for the therapeutic development of umbilical cord blood ...
Umbilical cord blood (UCB) is a primitive and abundant source of mesenchymal stem cells (MSCs). UCB-derived MSCs have a broad and efficient therapeutic capacity to treat various diseases and disorders.
Umbilical cord stem cells: Background, processing and …
2020年8月1日 · Umbilical cord, umbilical cord vein, amnion/placenta and Wharton’s jelly are all rich of many types of multipotent stem cell populations capable of forming many different cell types. This review will focus on umbilical cord stem cells processing and current application in …
Cord blood hematopoietic stem cell transplantation
2010年5月26日 · Umbilical cord blood (CB) is a clinically useful source of hematopoietic stem (HSC) and progenitor (HPC) cells for treatment of a wide variety of malignant and non-malignant disorders.
Human umbilical cord derived-mesenchymal stem cells alleviate …
2024年12月16日 · Mesenchymal stem cells (MSCs) are a type of adult stem cells with multidirectional differentiation capacity, strong immunomodulatory effects and low immunogenicity. MSCs could be extracted from various tissues, including umbilical cord, bone marrow, fat and dental pulp [7] .
From cord to caudate: characterizing umbilical cord blood stem cells ...
2017年11月1日 · Umbilical cord blood (UCB) is an attractive source of stem cells, since its collection is noninvasive, painless, and does not evoke the ethical concerns of embryonic stem cells....
Fresh Umbilical Cord Blood—A Source of Multipotent Stem Cells …
2023年8月23日 · Umbilical cord blood (UCB) is a rich source of hematopoietic cells that can be used to replace bone marrow components. Many blood disorders and systemic illnesses are increasingly being treated with stem cells as regenerative medical therapy.
Human umbilical cord mesenchymal stem cells improve the …
4 天之前 · This study aimed to investigate the functional role and mechanism of human umbilical cord mesenchymal stem cells (hUCMSCs) in the POI animal model through the PERK/eIF-2α/ATF4/CHOP pathway. ... Elam L, Elsharoud A, Al-Hendy A (2019) Umbilical cord blood mesenchymal stem cells as an infertility treatment for Chemotherapy Induced premature ...