The patient's medications should be analyzed closely for drug interactions with warfarin, especially when initiating or altering therapy. The effect of a drug interaction can be unpredictable; thus, individuals receiving interacting medications are likely to require increased INR monitoring.

Warfarin Interactions. There are 650 drugs known to interact with warfarin, along with 8 disease interactions, and 5 alcohol/food interactions. Of the total drug interactions, 163 are major, 417 are moderate, and 70 are minor.

2023年5月1日 · Warfarin's hepatic metabolism and protein binding are the most common mechanisms for the occurrence of drug-drug interactions. Warfarin is metabolized via the cytochrome P450 system by CYP 2C9, 1A2, and 3A4.

Complex interaction: initially ↑ INR, but then ↓ after prolonged administration. Additionally, warfarin may alter serum phenytoin concentrations. Expect 2- to 5-fold increase in warfarin dose requirements. A list of drugs that interact with warfarin.

The following list contains common medications that interact with warfarin (Coumadin), which may lead to decreased INR readings and thus, increased risk of clotting, strokes, and DVTs (i.e., blood is “not thin enough”).

2022年5月27日 · Both warfarin and direct oral anticoagulants are susceptible to drug-drug interactions (DDIs). DDIs are an important cause of adverse drug reactions and exact a large toll on the health care system.

There are 650 drugs known to interact with Coumadin (warfarin), along with 8 disease interactions, and 5 alcohol/food interactions. Of the total drug interactions, 163 are major, 417 are moderate, and 70 are minor.

2023年5月12日 · More than 200 medications, foods, and supplements can interact with warfarin. But don’t worry, we’ll help sort this all out. Here, we’ll cover 10 of the most important warfarin interactions to watch out for.

Comprehensive disease interaction information for warfarin systemic. Includes Oral anticoagulants - bleeding.

Talk to a healthcare provider if you are uncertain about what foods or medications you take that may interact with warfarin. It is important to tell your doctor about all medications you use, including vitamins and herbs. Do not stop using any medications without first …