Calmodulin - Wikipedia
Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. [1] It is an intracellular target of the secondary messenger Ca 2+, and the binding of Ca 2+ is required for the activation of calmodulin.
Calmodulin - Definition, Function and Structure - Biology Dictionary
2017年7月4日 · Calmodulin, or calcium-modulated protein, is a calcium-binding protein found in the cytoplasm of all eukaryotic cells. It interacts with many other proteins in the cell, and acts as a regulator or an effector molecule in a wide variety of cellular functions.
Molecule of the Month: Calmodulin - RCSB: PDB-101
Calmodulin changes shape when it binds to calcium and can activate over 300 essential proteins. Each of its four high-affinity calcium binding sites, called EF-hands, contains a characteristic loop flanked by two alpha helices.
Signaling: Calcium and Calmodulin - Chemistry LibreTexts
Calmodulin, or CaM, is a polypeptide that is ubiquitous in all eukaryotic cells. This protein is known as calmodulin because it is a cal cium- mod ulated prote in that plays a vital role in the process of calcium signal transduction.
Calmodulin – A Comprehensive Guide - Anatomy Notes
2024年8月16日 · Calmodulin is a small, multidomain protein composed of 148 amino acids. Its unique structure allows it to bind calcium ions efficiently. The protein features two globular lobes connected by a flexible linker region. Each lobe contains EF-hand motifs, specialized sequences that enable calcium binding.
Calmodulin - an overview | ScienceDirect Topics
Calmodulin is a multifunctional, intermediate calcium-binding messenger protein expressed in all eukaryotic cells and a major transducer of calcium signals. The authors concluded that binding of calmodulin to the target-SNARE synaptobrevin precedes the binding of synaptobrevin to acidic phospholipids of the plasma membrane, favoring fusion.
Calmodulin - an overview | ScienceDirect Topics
Calmodulin is the major intracellular calcium receptor regulating a multitude of physiological processes. Calmodulin regulates cell proliferation, programmed cell death and autophagy in higher eukaryotes. Calmodulin has a major impact on …
Calmodulin | Clinical Center - National Institutes of Health
Calmodulin is a ubiquitous, highly conserved protein that plays a critical role in numerous essential cellular functions, including Ca 2+ transport, cell motility, cytoskeletal assembly, protein phosphorylation/dephosphorylation, cell proliferation and cell cycle progression.
Calmodulin - an overview | ScienceDirect Topics
Calmodulin (CaM) is a small, cytoplasmic Ca 2+-binding protein that regulates cellular activities including protein kinases and ion channels. A notable property of the RyRs is their direct interaction with CaM in the absence and presence of Ca 2+.
Calmodulin Structure, Function & Examples - Study.com
2023年11月21日 · Calmodulin is a calcium-modulated protein that regulates the intracellular concentration of calcium. It does this by activating various proteins that either utilize or transport calcium.