A series of AIE active molecules based on barbituric acid were synthesized. In the aggregate state in THF/water, their emission color change from yellow to red. Molecular dynamics simulations show that TNB has the highest binding energy, which rationalize that TNB shows the strongest fluorescence intensity in the aggregate state.

Substituted chromeno-based barbituric acid derivatives were synthesized via MCR catalyzed by trisodium citrate dihydrate in EtOH under aqueous conditions. 4-Hydroxycoumarin 92 reacted with substituted benzaldehyde 39 along with substituted BA 93 to form compound 94 in excellent yields up to 95–98%.

A spectrophotometric method is applied to the estimation of barbituric acid, 1,3-dimethylbarbituric acid and thiobarbituric acid with 1,4-naphthoquinone in 50% methyl alcohol–water mixture. This method is simple, more sensitive and the color produced is stable for longer periods.

Be specific using barbituric acid as your example? Pink-purple color results when the p-DMBA complexes with the indole. After the condensation of one molecule of LSD with one molecule of p-dimethylamino benzaldehyde, the carbinole is formed.

Benzaldehyde (C 6 H 5 CHO) is an organic compound consisting of a benzene ring with a formyl substituent. It is among the simplest aromatic aldehydes and one of the most industrially useful. It is a colorless liquid with a characteristic almond -like odor , and is commonly used in cherry -flavored sodas . [ 5 ]