Hematopoietic stem cells are essential to haematopoiesis, the formation of the cells within blood. Hematopoietic stem cells can replenish all blood cell types (i.e., are multipotent) and self-renew. A small number of hematopoietic stem cells can expand to generate a very large number of daughter hematopoietic stem cells.

Hematopoietic stem cells (HSCs) are multipotent primitive cells that can develop into all types of blood cells, including myeloid-lineage and lymphoid-lineage cells (1). HSCs can be found in several organs, such as peripheral blood (PB), bone …

2017年2月6日 · Haematopoietic stem cells (HSC) are the architects of definitive haematopoiesis, that is, blood cell production that occurs continuously during the life of an organism.

2015年4月23日 · Hematopoietic stem cell (HSC) research took hold in the 1950s with the demonstration that intravenously injected bone marrow cells can rescue irradiated mice from lethality by reestablishing blood cell production.

4 天之前 · Hematopoietic stem cell transplantation (HSCT) is a promising approach in regenerative medicine and serves as a standard treatment for different malignant and non-malignant conditions. Despite its widespread applications, HSCT is associated with various complications that compromise patients’ lives and pose considerable risks of morbidity and …

Hematopoietic stem cell (HSC) regeneration is the remarkable process by which extremely rare, normally inactive cells of the bone marrow can replace an entire organ if called to do so by injury or harnessed by transplantation.

2014年12月1日 · Hematopoietic stem cells (HSC) or blood forming stem cells are adult stem cells that can develop into any of the three types of blood cells: red cells, white cells or platelets [3].

2023年8月10日 · Developmental hematopoiesis consists of multiple, partially overlapping hematopoietic waves that generate the differentiated blood cells required for embryonic development while establishing a pool of undifferentiated hematopoietic stem cells (HSCs) for …

2023年8月10日 · Hematopoietic stem cells (HSCs) are responsible for the lifelong production of all blood lineages; therefore, their specification and maintenance are tightly regulated. Many studies have leveraged murine models of hematopoiesis to provide basic insights into HSC biology and have defined HSCs based on murine cell surface markers, which are not ...

Hematopoietic stem cells (HSCs) constitute a rare population of cells at the foundation of the adult hematopoietic system. Through their ability to self-renew and to differentiate, HSCs are responsible for the continuous production of mature blood cells throughout life.