Laminin - Wikipedia
Laminins are heterotrimeric proteins with a high molecular mass (~400 to ~900 kDa) and possess three different chains (α, β, and γ) encoded by five, four, and three paralogous genes in …
13.5: Laminins - Biology LibreTexts
2022年12月30日 · Laminins are a family of secreted glycoproteins that are found in many ECM formations, and like fibronectin, bind to cells via integrin receptors. The laminin protein is …
Laminin - an overview | ScienceDirect Topics
Laminins are a family of glycoproteins that consist of one heavy α chain and two light β and γ chains (Timple, 1989). The laminin molecule is a major component of the basement …
The laminin family - PMC
Laminins are large molecular weight glycoproteins constituted by the assembly of three disulfide-linked polypeptides, the α, β and γ chains. The human genome encodes 11 genetically distinct …
Structural biology of laminins - PubMed
2019年9月13日 · Laminins are large cell-adhesive glycoproteins that are required for the formation and function of basement membranes in all animals. Structural studies by electron …
Laminins in Cellular Differentiation: Trends in Cell Biology - Cell …
2019年11月5日 · Basement membrane laminins (LNs) have been shown to modulate cellular phenotypes and differentiation both in vitro and during organogenesis in vivo. At least 16 …
Laminins: Roles and Utility in Wound Repair - PMC - PubMed …
Laminins, netrins, and LaNts are extracellular matrix (ECM) proteins and that makes them excellent candidate targets for therapy development, as any treatment modality can be directly …
Laminin - an overview | ScienceDirect Topics
Laminin is the main non-collagenous glycoprotein found in the basement membrane [1]. It is a heterotrimer of three subunits, α, β and γ held together by disulphide bonds to form a shape of …
Laminins | Cell and Tissue Research - Springer
2009年8月20日 · Laminins are cell adhesion molecules that comprise a family of glycoproteins found predominantly in basement membranes, which are the thin sheets of extracellular matrix …
Structural mechanism of laminin recognition by integrin
2021年6月29日 · Here, we report the structures of the prototypic laminin receptor α6β1 integrin alone and in complex with three-chain laminin-511 fragment determined via crystallography …