Understanding pressure and pressure-volume concepts helps to contextualize the hemodynamic assessment, since hemodynamics measure pressure and flow but fail to capture volume. The pressure-volume loop of the left ventricle (LV) operates within the space subtended by the end-systolic pressure-volume relationship (ESPVR; also known as end ...

During heart failure, myocardial contractility is reduced, which decreases the slope of the PRSW relationship. Recent studies also indicate that the volume axis intercept of the PRSW relationship (not the slope) may be a better indicator of the severity of contractile dysfunction.

Heart failure with reduced ejection fraction (HFrEF) is characterized by ventricular remodeling and impaired myocardial energetics. Left ventricular pressure-volume (PV) loop analysis can be performed noninvasively using cardiovascular magnetic resonance (CMR) imaging to assess cardiac thermodynamic efficiency.

To illustrate the pressure-volume relationship for a single cardiac cycle, the cycle can be divided into four basic phases: ventricular filling (phase a, diastole), isovolumetric contraction (phase b, systole), ejection (phase c, systole), and isovolumetric relaxation (phase d, diastole).

2020年6月14日 · A PV loop plots the changes in ventricular pressure associated with the changes in volume which occur during the cardiac cycle. Multiple pieces of information can be extracted from such a loop, including volumes (eg. stroke volume), pressures (eg. end-systolic pressure), and area (which represents myocardial work).

2021年12月29日 · RV pressure-volume analysis can help characterize RV physiology in a variety of conditions and clinical settings. HFpEF indicates heart failure preserved ejection fraction; HFrEF, heart failure reduced ejection fraction; LVAD, left ventricular assist device; and TAVR, transcatheter aortic valve replacement.

Penicka M, Bartunek J, Trakalova H, Hrabakova H, Maruskova M, Karasek J, et al. Heart failure with preserved ejection fraction in outpatients with unexplained dyspnea: a pressure-volume loop analysis.

In hemodynamic research, pressure-volume loops have long been understood to provide a much more complete understanding of cardiac performance due to the range of cardiac indices that can be measured beat-to-beat, the ability to measure pressure and volume simultaneously with great fidelity, and the characterization of cardiac performance rela-ti...

2019年11月25日 · The use of PV loops has enhanced our understanding and diagnosis of common conditions associated with heart failure. In addition, it has shown promise as an adjunct to therapeutic procedures.

2024年8月28日 · This article explores the significance of heart failure pressure-volume loops in diagnosing different types of heart failure and highlights the specific loop characteristics that indicate systolic or diastolic dysfunction.

2019年11月25日 · In hemodynamic research, pressure-volume loops have long been understood to provide a much more complete understanding of cardiac performance due to the range of cardiac indices that can be measured beat-to-beat, the ability to measure pressure and volume simultaneously with great fidelity, and the characterization of cardiac performance relativ...

Pressure-volume (PV) loops illustrating the physiology of a ventricular septal defect (VSD). The green PV loop represents the normal state, the purple loop represents an acute heart failure state, and the red loop represents a VSD in the setting of acute heart failure.

Heart failure caused by systolic dysfunction is referred to as heart failure with reduced ejection fraction (HFrEF). A loss of intrinsic inotropy on stroke volume and end-diastolic and end-systolic volumes is best depicted using ventricular pressure-volume loops (see figure).

Background: Left ventricular pressure-volume (LV-PV) loops provide comprehensive characterization of cardiovascular system in both health and disease, which are the essential element of the hemodynamic evaluation of heart failure (HF). This study attempts to achieve more detailed HF classifications by non-invasive LV-PV loops from ...

2024年10月7日 · One of the most insightful methods to examine heart function in systolic heart failure is by analyzing the pressure-volume loop. This graphical representation provides a comprehensive view of the changes in stroke volume, contractility, and overall left ventricular function in patients suffering from systolic heart failure.

We created single-beat PV loops by combining data from cine computed tomography (CT) and right heart catheterization in 44 heart failure patients, tested the approximations made by clinical RVSWI and found it to underestimate PV loop RVSWI, primarily due to …

2024年9月2日 · Understanding the effects of preload and afterload on the pressure-volume loop is essential for managing congestive heart failure. Elevated preload and afterload in CHF lead to significant alterations in the PV loop, reflecting the heart’s impaired function.

Graph showing the progression of heart failure by mean pressure volume loop for all American Heart Association (AHA)/American College of Cardiology (ACC) heart failure stages from O-D (various markers) along with the modelled loops (solid black lines).

In patients with progressively worse clinical heart failure (NYHA functional class II [Fig. 1B]; NYHA functional class III, [Fig. 1C]; NYHA functional class IV [Fig. 1D]), the loops shift progressively to the right toward larger volumes; a sign of progressive remodeling.

4 天之前 · Heart failure (HF) is one of the significant complications in patients with myocardial infarction (MI), leading to increased risk for cardiovascular morbidity and mortality.1 Left ventricular ejection fraction (LVEF) is a crucial parameter in HF assessment and management, although the differences in mortality are little different between HF with LVEF≥50% or HF with …

2024年9月10日 · The real-time analysis of the pressure-volume loop during cardiac catheterization allows healthcare professionals to identify abnormalities in ventricular compliance and relaxation, which are key to differentiating diastolic heart failure from other types of …