Pyrrole is a heterocyclic, aromatic, organic compound, a five-membered ring with the formula C 4 H 4 NH. [3] It is a colorless volatile liquid that darkens readily upon exposure to air. Substituted derivatives are also called pyrroles, e.g., N-methylpyrrole, C 4 H 4 NCH 3.

Pyrrole, any of a class of organic compounds of the heterocyclic series characterized by a ring structure composed of four carbon atoms and one nitrogen atom. The simplest member of the pyrrole family is pyrrole itself, a compound with molecular formula C4H5N.

The epsilon-amino groups of lysyl residues react with 2,5-hexanedione forming pyrrole adducts, followed by pyrrole-mediated protein crosslinking. Both reaction steps have been proposed as mechanisms causing neurofilament accumulation and acceleration of transport.

Pyrrole. Pyrrole is a five-membered heterocyclic ring which has 5 p orbitals and six pi electrons contributing to its aromaticity. Each carbon in pyrrole contributes one p orbital and pi electron. The nitrogen in pyrrole contributes two pi electrons by becoming sp 2 hybridized and placing its lone pair electrons into a p orbital. The ...

2024年9月30日 · Pyrrole (spelled with two r’s and one l) and imidazole are five-membered heterocycles, yet both have six π electrons and are aromatic.

Pyrrole is a compound of heterocyclic series which is characterized by a ring structure. The ring is composed of four carbon (C) atoms, five hydrogens (H) and one nitrogen(N) atom. The simplest compound of this type of family is pyrrole. The molecular formula of pyrrole is C 4 H 5 N. The system of the ring of pyrrole occurs in pigments of bile ...

Pyrrole is very much less basic than secondary amines but much more acidic. Pyrrole is, however, still a very weak acid (p K a = 17.5). The nitrogen-bound proton can be abstracted from pyrrole by the use of strong bases such as sodium amide …

2005年5月3日 · Pyrrole is a heterocyclic aromatic five membered multiple pharmacophoric template. • The name pyrrole came from the Greek word ‘pyrrols’ means fiery from the reaction. • Pyrroles exhibit lower basicity due to delocalization of …

Pyrrole is an important nitrogen-containing aromatic heterocycle that can be found in numerous compounds of biological and material significance. Given its vast importance, pyrrole continues to be an attractive target for the development of new synthetic reactions.

Abstract. 1H-pyrrole-2,5-dione derivatives are known for their wide range of pharmacological properties, including anti-inflammatory and antimicrobial activities.This study aimed to synthesize new 3,4-dimethyl-1H-pyrrole-2,5-dione derivatives 2a–2f in the reaction of N 3-substituted amidrazones with 2,3-dimethylmaleic anhydride and evaluate their structural and biological …