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Alzheimer's disease - plaques, tangles, causes, symptoms & pathology
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”Alzheimer’s disease is a neurodegenerative disorder involving extracellular plaques (amyloid-β) and intracellular tangles of tau protein. Recently, tangle formation has been identified as a major event involved in the neurodegenerative process, due to the conversion of either soluble peptides or oligomers into insoluble filaments. At present, the current therapeutic strategies are aimed at natural phytocomplexes and polyphenolics compounds able to either inhibit the formation of tau filaments
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“Alzheimer’s disease is a neurodegenerative disorder involving extracellular plaques (amyloid-β) and intracellular tangles of tau protein. Recently, tangle formation has been identified as a major event involved in the neurodegenerative process, due to the conversion of either soluble peptides or oligomers into insoluble filaments. At present, the current therapeutic strategies are aimed at natural phytocomplexes and polyphenolics compounds able to either inhibit the formation of tau filaments o
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Alzheimer’s disease is a progressive neurodegenerative disorder characterized by the destruction of around 100 billion neurons, leading to the loss of 100 trillion synaptic connections. The disease is marked by a gradual loss of cortical neurons, which plays a crucial role in cognitive functions such as memory, reasoning, and language. This neuronal loss leads to the accumulation of amyloid plaques, which are toxic clumps of beta-amyloid proteins that disrupt cell-to-cell communication in the br
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