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Antinuclear Antibody Test
A positive antinuclear antibody test means that antibodies are present in the blood that are targeting structures within the nucleus of cells. This can happen for a variety of reasons, but viral infections and certain seizure medications are possible causes. In some cases, a positive antinuclear antibody test can be indicative of an autoimmune disease, such as lupus or rheumatoid arthritis. Autoimmune diseases occurs when the body's immune system mistakenly attacks healthy tissue. This can cause
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A positive antinuclear antibody test means that antibodies are present in the blood that are targeting structures within the nucleus of cells. This can happen for a variety of reasons, but viral infections and certain seizure medications are possible causes. In some cases, a positive antinuclear antibody test can be indicative of an autoimmune disease, such as lupus or rheumatoid arthritis. Autoimmune diseases occurs when the body's immune system mistakenly attacks healthy tissue. This can cause
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SOLVED: Consider the use of the ANA (antinuclear antibody) test in the diagnosis of SLE (systemic lupus erythematosus). In a rheumatology practice, the prevalence of SLE in patients on whom an ANA test was done was 2.88% with a hypothetical population of 100,000 patients. The sensitivity of the ANA for SLE is 98% and the specificity is 93%. What are the True Positives, True Negatives, PPV, and NPV of the test? (Show all calculations)
SOLVED: Consider the use of the ANA (antinuclear antibody) test in the diagnosis of SLE (systemic lupus erythematosus). In a rheumatology practice, the prevalence of SLE in patients on whom an ANA test was done was 2.88% with a hypothetical population of 100,000 patients. The sensitivity of the ANA for SLE is 98% and the specificity is 93%. What are the True Positives, True Negatives, PPV, and NPV of the test? (Show all calculations)
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