Appendicitis Symptoms and Treatment Options | The appendix is a pouch that connects to the colon in your right, lower abdomen or belly. Appendicitis is inflammation or painful swelling of the... | By Marshfield Clinic Health System | Appendicitis happens when the base of the appendix gets clogged up and basically it kind of can't drain it drains into the colon typically it get clogged usually gets clogged up by you know lymphatic tissue for instance in the youngsters they get a cold or a virus s